The FA Cup quarter-final draw will be made after tonight’s games with Liverpool a glaring absentee.
Jurgen Klopp’s treble dream ended last night at the hands of Chelsea as goals from Willian and Ross Barkley sealed a 2-0 win.
Newcastle and Sheffield United both secured their place in the last eight with wins over West Brom and Reading respectively.
Arsenal , the competition’s most successful team, beat Portsmouth on Monday night to leave four spots left.
Manchester City will expect to see off Sheffield Wednesday at Hillsborough after Pep Guardiola named a strong team following their Carabao Cup success on Sunday.
Tottenham host Norwich and, despite some indifferent form, will be favourites to progress as they target a ninth FA Cup success and their first since 1991.
Wayne Rooney takes on his former team with Derby as Manchester United travel to Pride Park. The Rams secured a shock win over the Red Devils in the cup last term and will hope for a repeat.
Leicester, who have had to deal with a dip in form recently, take on Championship outfit Birmingham as they target silverware under Brendan Rodgers.
Many believe the FA Cup has lost its magic over the past few years but it is regularly one by one of the Premier League’s top six.
The table topping Reds are the only one of those six to have been knocked out prior to Wednesday’s kick-offs and by the end of the night all eight quarter finalists could be top flight clubs.